Vyleesi Injection in the Philippines: Women’s Low Libido & Men’s Experimental Use

2 Dec 2025

Vyleesi Injection in the Philippines: What Women and Men Should Know

Imagine a discreet self-injection that could help reignite sexual desire — when you choose. That’s the promise of Vyleesi (bremelanotide), a drug officially approved in the U.S. for women with low libido. But what about men? Let’s explore its potential, availability, and cautions in the Philippines.

For Women: Official Use

Vyleesi is approved for premenopausal women diagnosed with Hypoactive Sexual Desire Disorder (HSDD) — persistent low sexual desire that causes distress.

Mechanism: Vyleesi is a melanocortin receptor agonist, acting on brain receptors that influence sexual desire rather than directly affecting hormones or blood flow.
Administration: Self-injected under the skin in the abdomen or thigh about 45 minutes before sexual activity.
Frequency: Maximum of 8 doses per month, with at least 24 hours between doses.
Reported effects: Many women experience increased sexual interest and reduced distress related to low desire.
Common side effects: Nausea, flushing, headache, dizziness, injection-site reactions, temporary increases in blood pressure, and possible skin darkening (hyperpigmentation). Women with uncontrolled hypertension or cardiovascular disease should avoid Vyleesi.
Availability in the Philippines: As of 2025, Vyleesi is not registered locally, so it cannot be legally obtained from clinics or pharmacies. Importing it independently carries legal and safety risks.

For Men: Experimental, Off-Label Use

Though Vyleesi is not approved for men, some studies and anecdotal reports suggest potential off-label benefits for men with:

Erectile dysfunction
Low sexual desire
Performance anxiety

Preliminary findings: Men using bremelanotide off-label reported:

Improved erectile function
Increased sexual interest and satisfaction
Ability to achieve additional erections up to 18–24 hours after injection

Important caveats:

Male use is off-label and experimental.
Safety and efficacy for male sexual dysfunction are not fully established.
Official guidance warns against using Vyleesi for “enhancing sexual performance” in men.

Men in the Philippines should only consider experimental use under strict medical supervision, understanding the uncertain benefits and risks.

Alternatives in the Philippines

Since Vyleesi is not legally available for women and experimental for men, safer alternatives include:

Lifestyle improvements: Exercise, stress reduction, adequate sleep, and emotional well-being.
Therapy and counseling: For relationship issues, sexual anxiety, or emotional barriers to intimacy.
Medical consultation: Hormone evaluation, medication review, or other approved treatments.

These approaches are safe, legally accessible, and often effective at improving sexual desire and satisfaction.

Takeaway

For women: Vyleesi is a novel, on-demand option for restoring sexual desire, but it is not yet accessible in the Philippines.

For men: Preliminary evidence suggests potential benefits, but it is off-label and unapproved, so caution is essential.

In both cases, the safest path is professional guidance combined with lifestyle or therapeutic support. Awareness, education, and safe, evidence-based practices remain key to sexual wellness in the Philippines.