You’ve heard of the morning-after pill for pregnancy prevention — but what if there were a morning-after pill for STIs? Great news: there is. Say hello to DoxyPEP — a powerful new tool in sexual health that’s helping people take charge, stay safe, and enjoy their sex lives with more peace of mind.
DoxyPEP (short for Doxycycline Post-Exposure Prophylaxis) is a single dose of doxycycline — a widely used antibiotic — taken within 72 hours after sex to reduce the risk of acquiring certain bacterial STIs, like:
It’s not a vaccine, and it doesn’t replace condoms or regular STI screening — but it’s a game-changer for people at higher risk of exposure.
Think of DoxyPEP like your secret sidekick — swooping in after the action to stop bacterial infections before they take hold. By flooding your system with a short burst of targeted antibiotic protection, it disrupts bacteria before they can establish an infection.
Clinical studies have shown that DoxyPEP can reduce:
It’s already being used by people in certain communities — like men who have sex with men (MSM) and transgender women — who have a higher risk of recurrent STIs.
As with any antibiotic, it’s important to use DoxyPEP responsibly to avoid contributing to antibiotic resistance. That’s why it’s recommended for people with frequent STI exposure, not necessarily for everyone.
You might benefit from DoxyPEP if:
Talk to a healthcare provider to see if it’s right for you. It’s not a replacement for safe sex practices, but it's an added layer of protection for those who need it most.
DoxyPEP empowers people to enjoy intimacy without the worry. It’s a sign of the times: science working with real-life needs. If you're active, informed, and health-conscious, DoxyPEP could be your next smart move.