The Silent Signs of STI-Linked Gut Infections—and How to Treat Them

8 May 2025

Down There Feeling a Little... Off? It Might Be More Than Just Taco Night. Understanding and Treating Proctitis, Proctocolitis, and Enteritis Caused by STIs

Let’s talk about the uncomfortable truth that nobody really wants to bring up at brunch: your gut and your sex life are more connected than you think.

From itchy discomfort to bathroom-related panic, STI-related inflammation in your lower digestive tract isn’t just awkward—it’s a medical issue that deserves real answers, real treatment, and zero shame.

The Sexy Science: What’s Really Going On?

When sexually transmitted infections (STIs) spread beyond their usual zones, they can invade your gastrointestinal tract—especially if you're engaging in receptive anal sex. And when they do, they can cause:

Proctitis: Inflammation of the rectum. Think rectal pain, bleeding, discharge, and feeling like you constantly need to go.
Proctocolitis: Involves both the rectum and the colon. Cue cramps, bloody diarrhea, and an urgent need to sprint to the bathroom.
Enteritis: Less common, but STIs like HIV, CMV, or parasites can affect the small intestine, too—leading to diarrhea, fever, and fatigue.

Which STIs Are the Culprits?

These aren’t your everyday sniffles. The most common STI-related causes include:

Chlamydia (especially LGV – Lymphogranuloma Venereum subtype)
Gonorrhea
Herpes simplex virus (HSV)
Syphilis
HIV
Cytomegalovirus (CMV)
Shigella and other enteric infections (transmitted through oral-anal contact)

These infections can be passed even when partners don’t show symptoms, which is why regular STI screenings are so important.

Treatment Options: Fast, Private, Effective

At PULSE CLINIC (Social Enterprise), we offer inclusive, judgment-free sexual health care across Asia—specialized for diverse identities and lifestyles. Whether you're seeking answers, treatment, or just a safe place to ask questions, we're here.

1. Accurate Diagnosis Is Key

Rectal swabs and stool tests
Blood work for viral infections
Colonoscopy (in severe or persistent cases)

2. Targeted Medications

Antibiotics for gonorrhea, chlamydia, and syphilis
Antivirals for herpes and CMV
Anti-inflammatory treatments if the irritation persists

3. Relief + Recovery

Pain relief (because no one should wince while sitting)
Hydration and probiotics to restore balance
Nutritional support for gut healing

4. Partner Notification and Prevention Support

We provide friendly, confidential tools to help notify partners anonymously, along with sexual health education and safer sex kits.

Ready to Feel Like Yourself Again?

Don't let discomfort or stigma keep you from getting the care you need. PULSE CLINIC (Social Enterprise) is ready to support your sexual health journey—online or in person.